SERVICESGENE TO PROTEIN
From custom DNA to engineered proteins
Gene design and optimisation, synthetic genes, subcloning, plasmid preparation, protein
expression optimisation, recombinant protein production, purification and characterisation. CELL AND GENOME ENGINEERING – STABLE CELL LINES From custom cells and target genes to engineered stable cell lines
Non-viral vector-based stable transgenic cell lines (antibiotic selection)
Targeted genome editing and global genome positioning technology-based cell line generation
KO, KI, point mutations, deletions, multiple transgenic and engineered cell lines for research, bioassays, protein production. MONOCLONAL ANTIBODIES From custom antigen sequence to specific mouse monoclonal antibodies
Epitope design, peptide synthesis, immunisation, hybridoma generation and screening, antibody production, purification and characterisation. CYTOKINE PRODUCTION Custom cytokine gene design and optimisation, gene synthesis, cloning into expression vectors, expression, purification and biochemical/biological characterisation of your recombinant cytokines. PROTEIN ENGINEERING (mutagenesis, IVE, structure-based design) PHAGE DISPLAY TECHNOLOGY (peptide and protein display libraries) HIGH THROUGHPUT SCREENING (Tecan) LARGE SCALE FERMENTATION (2-100 L bacterial, 2-10 L mammalian)
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Links & Partnes
Links & Partners
Magyar Gazdaságfejlesztési Központ
Center for Clinical Genomics and Personalised medicine
Nuclear Hormon Receptor Research Laboratory - NLAB
Department of Biochemistry and Molecular Biology
Medical and Health Science Center
Research Center for Molecular Medicine