CORE FACILITYThe Laboratory has flexible capacities to take in projects from research groups within the University of Debrecen. We are offering RESEARCH & DEVELOPMENT COLLABORATIONS - subject to joint grant application or with a minimum contribution of 50% of all costs incurred by the project in question. JOINT GRANT APPLICATIONS - we encourage researchers to incorporate costs of core services into grant applications, based on our cost estimate, or to nominate us in the applications as partners. CONSULTATION - we are happy to help you in designing joint projects, or give scientific advise in your projet design to a limited extent, depending on available capacities. SERVICES - we provide services based on rigorous project design and cost calculation - see SERVICES menu item for more information on possibilities. PRODUCTS - we have ready-made products (cytokines, recombinant proteins) - see PRODUCTS menu items for more information - and have a strong pipeline and workflow for new product developments to meet your needs (e.g. custom cytokine production development - you name a cytokine, we produce it for you with QC within a couple of months).
Please, have a look at our INFRASTRUCTURE and TECHNOLOGIES for infromation on our capacities, competencies and possibilities.
COLLABORATIVE AND SERVICE PROJECT EXAMPLES (SINCE 2010) - UNIVERSITY OF DEBRECEN and its SPIN-OFF COMPANIES - Purification and characterisation (Western) of a rabbit polyclonal anti-SMRT antibody - Cloning and expression of an Fc-fusion protein. - Production and purification of PNGase F enzyme in E. coli for glycoanalytic applications. - Production and purification of human TG2 in HEK293T cell line using transient transfection. - Production of recombinant human IL.-4, GM-CSF, LIF etc. for monocyte differentiation into dendritic cell and ES cell culture sustainance. - Purification of -anti-TG2 minibodies produced in HEK293T cells. - Purification of mouse monoclonal antibodies from hybridoma culture supernatants. - ChIP-grade mouse monoclonal anti-RARa antibody development, purification and characterisation (Western, ChIP-qPCR, ChIP-Seq) - Peptide phage display library-base epitope mapping of tear protein depletion antibodies. - Soluble receptor detection (Western) and quantification ( ELISA,) in culture supernatants and patient samples.
For references, see the COLLABORATIONS section.
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Links & Partners
Magyar Gazdaságfejlesztési Központ
Center for Clinical Genomics and Personalised medicine
Nuclear Hormon Receptor Research Laboratory - NLAB
Department of Biochemistry and Molecular Biology
Medical and Health Science Center
Research Center for Molecular Medicine