Menu

Links & Partnes

Links & Partners

Magyar Gazdaságfejlesztési Központ

MAG_Zrt_logo

Center for Clinical Genomics and Personalised medicine

Genomics_logo

Nuclear Hormon Receptor Research Laboratory - NLAB

NLAB_logo

Department of Biochemistry and Molecular Biology

Medical and Health Science Center

DE_OEC_logo

Research Center for Molecular Medicine

rcmm_LOGO

University of Debrecen

UD_logo

UD-GenoMed Medical Genomic Technologies Ltd

UDG_logo

 

HLBS

HLBS_logo

Customers' Wishlist

I need

... a custom stable cell line!

... purified recombinant proteins!

... a custom monoclonal antibody!

... cytokines for my research!

... engineered proteins!

... a protein with novel functions!

Contact PROXENCELL

Dr. Zsolt Keresztessy, PhD MBA
Protein Expression and Cell Engineering Laboratory
Center for Clinical Genomics and Personalised Medicine
Nagyerdei krt 98, Debrecen H-4032 Hungary
Tel: +36 52 411 717 / 50226, 50206
e-mail: zsolt.keresztessy@med.unideb.hu
Find us:
Room 3.2.5 and Lab3.26, IVDI Building, Medical and Health Sciences Center

ORDERING INFO: LINK

 

News

Protein Expression Services

Protein expression services are opening for the University of Debrecen from May 2012.

Recombinant Human IL-4

Recombinant human IL-4 is available for purchase either in the form of IL-4 containing culture medium (use 1:10 dilution) or in purified form. The protein is produced in HEK293T cells, batch-tested by Western blotting, ELISA, TF-1 proliferation assay, and against endotoxins. See product sheet. Please, order online.

Polyclonal anti-SMRT antibody

Rabbit polyclonal anti-SMRT antibody is available for purchase. The antibody is protein-A purified, Western, IP, IHC, ChIP tested. See product sheet.

 

CORE FACILITY

The Laboratory has flexible capacities to take in projects from research groups within the University of Debrecen. 

We are offering

RESEARCH & DEVELOPMENT COLLABORATIONS - subject to joint grant application or with a minimum contribution of 50% of all costs incurred by the project in question.

JOINT GRANT APPLICATIONS - we encourage researchers to incorporate costs of core services into grant applications, based on our cost estimate, or to nominate us in the applications as partners.

CONSULTATION - we are happy to help you in designing joint projects, or give scientific advise in your projet design to a limited extent, depending on available capacities.

SERVICES - we provide services based on rigorous project design and cost calculation  - see SERVICES menu item for more information on possibilities.

PRODUCTS - we have ready-made products (cytokines, recombinant proteins) - see PRODUCTS menu items for more information - and have a strong pipeline and workflow for new product developments to meet your needs (e.g. custom cytokine production development - you name a cytokine, we produce it for you with QC within a couple of months).

 

Please, have a look at our INFRASTRUCTURE and TECHNOLOGIES for infromation on our capacities, competencies and possibilities.

 

COLLABORATIVE AND SERVICE PROJECT EXAMPLES (SINCE 2010) - UNIVERSITY OF DEBRECEN and its SPIN-OFF COMPANIES

- Purification and characterisation (Western) of a rabbit polyclonal anti-SMRT antibody

- Cloning and expression of an Fc-fusion protein. 

- Production and purification of PNGase F enzyme in E. coli for glycoanalytic applications.

- Production and purification of human TG2 in HEK293T cell line using transient transfection.

- Production of recombinant human IL.-4, GM-CSF, LIF etc. for monocyte differentiation into dendritic cell and  ES cell culture sustainance.

- Purification of -anti-TG2 minibodies produced in HEK293T cells.

- Purification of mouse monoclonal antibodies from hybridoma culture supernatants.

- ChIP-grade mouse monoclonal anti-RARa antibody development, purification and characterisation (Western, ChIP-qPCR, ChIP-Seq)

- Peptide phage display library-base epitope mapping of tear protein depletion antibodies.

- Soluble receptor detection (Western) and quantification ( ELISA,) in culture supernatants and patient samples.

 

For references, see the COLLABORATIONS section.

 

Please, contact us for details: Ezt a címet a spamrobotok ellen védjük. Engedélyezze a Javascript használatát, hogy megtekinthesse.

Gene-to-Protein Services

We deliver full service from custom DNA sequence to purified recombinant protein. Individually available service components are cloning, expression, purification, and characterisation of your protein of interest.

Read more>

Stable Cell Line Development

We offer state-of-the-art Cell and Genome Engineering technologies to generate custom stable cell lines for research, bioassays and protein production. Site-specific gene mutations, deletions, insertions, gene insertions, multiple transgenic cell lines.

Read more>

Monoclonal antibody development

You provide a custom target sequence – we produce specific mouse monoclonal antibodies.
Epitope design, peptide synthesis, immunisation, hybridoma generation and screening, antibody production, purification and characterisation.

Read more>

Cytokine Development Services

If you need a cytokine at an affordable price for your research - we  produce it for you. The workflow includes gene design and optimisation, gene synthesis, cloning into expression vectors, expression, purification and biochemical/biological characterisation of your recombinant cytokines.

Read more>

Recombinant proteins

We offer special services and consultation in the field of custom recombinant protein development, engineering, design, and evolution, including mutagenesis, library generation, directed molecular evolution, phage display technology, HTS screening.

Read more>

Antibodies and cytokines at great prices

Cytokine products:
human IL-4, IL-2, GM-CSF,
mouse IL-4
Coming soon: LIF, IL-9, IL-15

Read more>